Search results for "pandemic influenza"

showing 6 items of 6 documents

Vaccination against the 2009 pandemic influenza A (H1N1) among healthcare workers in the major teaching hospital of Sicily (Italy)

2011

The aim of the study was to investigate factors involved in vaccination acceptance among healthcare workers (HCWs) and adverse reactions rates associated with pandemic influenza vaccination. The study was carried out in the major teaching hospital of Sicily from November 2009 to February 2010 on 2267 HCWs. A total of 407 (18%) HCWs were vaccinated against the 2009 pandemic influenza A (H1N1). A logistic regression analysis indicates an increased risk of non-vaccination against pandemic influenza in females (OR = 1.6; 95% CI = 1.3-2.1) compared to males, in nurses/technicians/administrative workers (OR = 1.7; 95% CI = 1.3-2.2) compared to doctors/biologists, and in HCWs who were non-vaccinat…

AdultMalePandemic influenza vaccination healthcare workers adverse reactionsHealth PersonneleducationOrthomyxoviridaeSettore MED/42 - Igiene Generale E Applicatamedicine.disease_causeTeaching hospitalSurveys and QuestionnairesEnvironmental healthInfluenza HumanHealth careInfluenza A virusmedicineHumansHospitals TeachingAdverse effectSicilyGeneral VeterinaryGeneral Immunology and Microbiologybiologybusiness.industryVaccinationPublic Health Environmental and Occupational HealthPandemic influenzavirus diseasesMiddle Agedbiology.organism_classificationVaccinationLogistic ModelsInfectious DiseasesInfluenza VaccinesMultivariate AnalysisImmunologyMolecular MedicineFemaleViral diseasebusinessVaccine
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Effectiveness of pandemic and seasonal influenza vaccines in preventing pandemic influenza-associated hospitalization.

2011

Vaccines are leading pharmacological measures for limiting the impact of pandemic influenza in the community. The objective of this study was to investigate the effectiveness of influenza (pandemic and seasonal) vaccines in preventing pandemic influenza-associated hospitalization. We conducted a multicenter matched case-control study in 36 Spanish hospitals. Patients hospitalized with confirmed pandemic influenza between November 2009 and February 2010 and two hospitalized controls per case, matched according to age, date of hospitalization and province of residence, were selected. Multivariate analysis was performed using conditional logistic regression. Subjects were considered vaccinated…

AdultMalePediatricsmedicine.medical_specialtyMultivariate analysisAdolescentSeasonal influenzaYoung AdultPandemicInfluenza HumanMedicineHumansYoung adultChildAgedAged 80 and overGeneral VeterinaryGeneral Immunology and Microbiologybusiness.industryPublic Health Environmental and Occupational HealthPandemic influenzaCase-control studyInfant Newbornvirus diseasesInfantMiddle AgedHospitalsVaccinationHospitalizationInfectious DiseasesInfluenza VaccinesSpainCase-Control StudiesChild PreschoolImmunologyHuman mortality from H5N1Molecular MedicineFemalebusinessVaccine
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Pandemic influenza A (H1N1) infection in pregnant and nonpregnant women in Spain (2009-2010)

2014

The present study aimed to compare the main features of infection with pandemic influenza A virus in pregnant and nonpregnant women admitted to hospitals in Spain during the first waves of the 2009-2010 influenza pandemic. This was a prospective (November 2009 to June 2010), multicenter observational study. All cases were women of reproductive age who had not been vaccinated against seasonal or pandemic influenza A. Influenza infection was confirmed by reverse transcription-polymerase chain reaction (RT-PCR). The sociodemographic and clinical data of all cases were reviewed. A total of 219 inpatients, including 49 pregnant women and 170 nonpregnant women, were enrolled in the study upon adm…

AdultMicrobiology (medical)medicine.medical_specialtyAdolescentmedicine.drug_classAntibioticsDonesReproductive ageInfluenzavirusVirusYoung AdultEmbarassadesInfluenza A Virus H1N1 SubtypePregnancyInternal medicineInfluenza HumanmedicineHumansInfluenza virusesWomenPregnancy Complications InfectiousPandemicsRespiratory distressbusiness.industryPregnant womenPandemic influenzaGeneral MedicineInfluenza pandemicInfectious DiseasesIncreased riskSpainCase-Control StudiesFemaleObservational studybusiness
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Molecular surveillance of pandemic influenza A(H1N1) viruses circulating in Italy from May 2009 to February 2010: association between haemagglutinin …

2010

Haemagglutinin sequences of pandemic influenza A(H1N1) viruses circulating in Italy were examined, focusing on amino acid changes at position 222 because of its suggested pathogenic relevance. Among 169 patients, the D222G substitution was detected in three of 52 (5.8%) severe cases and in one of 117 (0.9%) mild cases, whereas the D222E mutation was more frequent and evenly distributed in mild (31.6%) and severe cases (38.4%). A cluster of D222E viruses among school children confirms reported human-to-human transmission of viruses mutated at amino acid position 222.

MaleMolecular surveillance; Pandemic influenza A(H1N1); Haemagglutinin mutations; Italy from May 2009 to February 2010pandemic influenzasurveillance of pandemic influenza A(H1N1); Molecular surveillance; pandemic influenzaEpidemiologyvirusesHaemagglutinin mutationssurveillance of pandemic influenza A(H1N1)Settore MED/42 - Igiene Generale E Applicatamedicine.disease_causeSeverity of Illness IndexInfluenza A Virus H1N1 SubtypePandemic influenza A(H1N1)PandemicInfluenza A VirusA(H1N1)ChildMutationReverse Transcriptase Polymerase Chain ReactionTransmission (medicine)Adolescent; Adult; Age Distribution; Aged; Amino Acid Substitution; Child; Child Preschool; Female; Hemagglutinins; Humans; Infant; Influenza A Virus H1N1 Subtype; Influenza Human; Italy; Male; Middle Aged; Mutation; Population Surveillance; Reverse Transcriptase Polymerase Chain Reaction; Severity of Illness Index; Sex Distribution; Young Adult; PandemicsMiddle AgedItaly from May 2009 to February 2010Molecular surveillance; pandemic influenza; A(H1N1); Italy; haemagglutinin mutationsHemagglutininsMolecular surveillanceItalyChild PreschoolPopulation SurveillanceFemaleHumanAdultAdolescentBiologyDisease clusterDisease courseYoung AdultAge DistributionVirologyInfluenza HumanmedicineHumansH1N1 SubtypeSex DistributionPreschoolhaemagglutinin mutationsPandemicsAgedMolecular epidemiologyPublic Health Environmental and Occupational HealthPandemic influenzaInfantVirologyInfluenzaMutational analysisAmino Acid SubstitutionMutationEurosurveillance
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Economic Evaluation of Health Services Costs During Pandemic Influenza A (H1N1) Pdm09 Infection in Pregnant and Non-Pregnant Women in Spain

2016

Background: The healthcare and socio-economic burden resulting from influenza A (H1N1) pdm09 in Spain was considerable. Our aim was to estimate and compare the management (resource utilization) and economic healthcare impact in an at-risk group of unvaccinated pregnant women with an unvaccinated group of non-pregnant woman of childbearing age (15-44 yr old). Methods: We addressed this question with a longitudinal, observational, multicentre study. Inputs were the requirements in managing both groups of women. Outcome measures were healthcare costs. Direct healthcare (including medical utilisation, prescriptions of antivirals, medication, diagnostic tests, and hospitalisation) costs and indi…

SpainPregnant womenlcsh:Public aspects of medicineOriginal Articlelcsh:RA1-1270Pandemic influenza A (H1N1)reproductive and urinary physiologyHealth servicesCosts
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Pandemic influenza A/H1N1 virus in a swine farm house in Sicily, Italy.

2012

This report describes a pandemic A/H1N1 (H1N1 pdm) virus outbreak occurred in December, 2009 in a swine farm used as research facility (Istituto Mediterraneo Trapianti e Terapie ad Alta Specializzazione) for preclinical studies, located in Sicily, Italy. All the 13 pigs of the farm, showed cough, fever, inappetence and weakness. At the same time, an unvaccinated worker of the stabling showed influenza-like symptoms. RNAv extracted from two swabs collected from infected pigs resulted positive by Real Time RT-PCR for Influenza A virus. Furthermore, after growth on embryonated eggs, viral isolates were identified by Real Time RT-PCR specific for H1N1 pdm virus and characterized antigenically. …

Swine DiseasesReverse Transcriptase Polymerase Chain ReactionSwineA/H1N1 viruReal-Time Polymerase Chain ReactionDisease OutbreaksZoonosisInfluenza A Virus H1N1 SubtypeOrthomyxoviridae InfectionsInfluenza HumanAnimalsHumansSequencingFemalePandemicsSicilyPandemic influenza
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